
Focus
DSIP
Delta Sleep-Inducing Peptide studied for deep sleep regulation, cortisol modulation, and neuroprotection.
Research Use Only: NuveraPeptides products are intended for laboratory and scientific research purposes only.
Purchase option
DSIP (Delta Sleep-Inducing Peptide) is a nonapeptide first isolated from rabbit cerebral venous blood in 1977. It crosses the blood-brain barrier and has been studied for its effects on delta wave sleep induction, HPA axis modulation (reducing stress-associated cortisol elevation), and neuroprotective signaling. DSIP acts on multiple systems including opiate, serotonin, and glucocorticoid pathways, making it a broad research tool in sleep biology and stress neuroscience. Each vial contains 10mg at ≥99% purity.
What it does
- Nonapeptide with BBB penetration in research models
- 10mg lyophilized powder — ≥99% purity verified
- Studied for delta wave sleep induction and cortisol modulation
- Third-party tested by ISO-certified laboratory
- Cold-chain shipped with Certificate of Analysis
How to use
Reconstitute with 1–2mL bacteriostatic water. Swirl gently until fully dissolved.
Store lyophilized at 2–8°C. Once reconstituted, refrigerate and use within 30 days.
For research use only.
What’s in the box
- 1 lyophilized vial
- Certificate of Analysis
- Desiccant pack
Product FAQ
Delta Sleep-Inducing Peptide. It was named for its ability to induce delta (slow-wave) EEG activity in early rabbit research studies.
Research suggests DSIP reduces excessive CRH (corticotropin-releasing hormone) release and normalizes elevated cortisol during stress, acting as a modulatory brake on the hypothalamic-pituitary-adrenal axis.
DSIP is not a direct sedative. It is studied as a sleep-quality modulator that promotes deeper sleep architecture rather than simply inducing sedation.