Vitality
KPV
Anti-inflammatory tripeptide derived from alpha-MSH studied for epithelial barrier and wound healing.
Research Use Only: NuveraPeptides products are intended for laboratory and scientific research purposes only.
Purchase option
KPV (Lys-Pro-Val) is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (α-MSH). It retains the anti-inflammatory activity of the full α-MSH peptide while offering greater stability and simpler synthesis. KPV acts through melanocortin receptors and NF-κB pathway inhibition, making it a useful research tool in inflammatory bowel models, skin barrier research, and wound healing biology. Each vial contains 10mg at ≥99% purity.
What it does
- C-terminal tripeptide of alpha-MSH (Lys-Pro-Val)
- 10mg lyophilized powder — ≥99% purity verified
- NF-κB inhibitory and melanocortin receptor activity
- Third-party tested by ISO-certified laboratory
- Cold-chain shipped with Certificate of Analysis
How to use
Reconstitute with 1–2mL bacteriostatic water. Swirl gently until dissolved.
Store lyophilized at 2–8°C. Once reconstituted, refrigerate and use within 30 days.
For research use only.
What’s in the box
- 1 lyophilized vial
- Certificate of Analysis
- Desiccant pack
Product FAQ
KPV is the terminal three amino acids (Lys-Pro-Val) of α-MSH. Researchers identified it as the minimal sequence required for α-MSH's anti-inflammatory activity.
KPV inhibits NF-κB activation, downregulates pro-inflammatory cytokines (IL-1β, IL-6, TNF-α), and activates melanocortin receptors involved in anti-inflammatory signaling.
KPV is relatively stable. Store reconstituted solution at 2–8°C and use within 30 days. Lyophilized form is stable for 24+ months when refrigerated.